Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC7A11Solute carrier family 7 member 11. (503 aa)    
Predicted Functional Partners:
SLC3A2
Solute carrier family 3 member 2.
   
 0.999
GPX4
Uncharacterized protein.
   
  
 0.869
CD44
CD44 molecule (Indian blood group).
    
 
 0.830
ENSCHIP00000001374
Uncharacterized protein.
    
 
 0.816
OTUB1
Ubiquitin thioesterase.
    
 
 0.816
ACSL4
Acyl-CoA synthetase long chain family member 4.
   
 
 0.804
FTH1
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
    
 
 0.755
NFE2L2
Nuclear factor erythroid 2-related factor 2.
    
 0.663
TFRC
Transferrin receptor.
      
 0.661
LOC102172435
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
    
 
 0.659
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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