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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPL2CSignal peptide peptidase like 2C. (686 aa)    
Predicted Functional Partners:
MAPT
Microtubule-associated protein.
      
 0.716
TEX36
Testis expressed 36.
      
 0.610
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit.
      
 0.551
CRHR1
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.550
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
      
 0.547
STK11IP
Serine/threonine kinase 11 interacting protein.
   
    0.499
GLT6D1
Glycosyltransferase 6 domain containing 1.
      
 0.493
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.483
TMEM74
Transmembrane protein 74.
      
 0.479
PRSS58
Serine protease 58.
   
  
 0.477
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.