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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)    
Predicted Functional Partners:
NHS
NHS actin remodeling regulator.
   
 0.684
TRIP11
Thyroid hormone receptor interactor 11.
    
 0.589
ZMYM4
Zinc finger MYM-type containing 4.
   
  0.581
PCM1
Pericentriolar material 1.
    
 0.537
YWHAH
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family.
    
 0.515
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.493
ZWILCH
Zwilch kinetochore protein.
    
 
 0.480
QSER1
Glutamine and serine rich 1.
   
  
 0.479
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
  
0.474
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.455
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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