TNFRSF18 protein (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTLA	CD40LG	ENSCHIP00000026139	ENSCHIP00000000228	B and T lymphocyte associated.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.635
BTLA	CTLA4	ENSCHIP00000026139	ENSCHIP00000003886	B and T lymphocyte associated.	Cytotoxic T-lymphocyte associated protein 4.	0.833
BTLA	FOXP3	ENSCHIP00000026139	ENSCHIP00000012575	B and T lymphocyte associated.	Forkhead box P3.	0.537
BTLA	ICOS	ENSCHIP00000026139	ENSCHIP00000030042	B and T lymphocyte associated.	Inducible T cell costimulator.	0.788
BTLA	TIGIT	ENSCHIP00000026139	ENSCHIP00000022175	B and T lymphocyte associated.	T cell immunoreceptor with Ig and ITIM domains.	0.783
BTLA	TNFRSF18	ENSCHIP00000026139	ENSCHIP00000001378	B and T lymphocyte associated.	Uncharacterized protein.	0.756
BTLA	TNFRSF4	ENSCHIP00000026139	ENSCHIP00000021531	B and T lymphocyte associated.	TNF receptor superfamily member 4.	0.545
BTLA	TNFSF14	ENSCHIP00000026139	ENSCHIP00000023208	B and T lymphocyte associated.	TNF_2 domain-containing protein.	0.695
BTLA	TNFSF15	ENSCHIP00000026139	ENSCHIP00000028593	B and T lymphocyte associated.	TNF superfamily member 15.	0.515
CD40LG	BTLA	ENSCHIP00000000228	ENSCHIP00000026139	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	B and T lymphocyte associated.	0.635
CD40LG	CTLA4	ENSCHIP00000000228	ENSCHIP00000003886	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Cytotoxic T-lymphocyte associated protein 4.	0.890
CD40LG	FOXP3	ENSCHIP00000000228	ENSCHIP00000012575	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Forkhead box P3.	0.853
CD40LG	ICOS	ENSCHIP00000000228	ENSCHIP00000030042	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Inducible T cell costimulator.	0.994
CD40LG	TIGIT	ENSCHIP00000000228	ENSCHIP00000022175	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	T cell immunoreceptor with Ig and ITIM domains.	0.519
CD40LG	TNFRSF18	ENSCHIP00000000228	ENSCHIP00000001378	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.756
CD40LG	TNFRSF4	ENSCHIP00000000228	ENSCHIP00000021531	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF receptor superfamily member 4.	0.531
CD40LG	TNFSF14	ENSCHIP00000000228	ENSCHIP00000023208	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein.	0.610
CD40LG	TNFSF15	ENSCHIP00000000228	ENSCHIP00000028593	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF superfamily member 15.	0.462
CTLA4	BTLA	ENSCHIP00000003886	ENSCHIP00000026139	Cytotoxic T-lymphocyte associated protein 4.	B and T lymphocyte associated.	0.833
CTLA4	CD40LG	ENSCHIP00000003886	ENSCHIP00000000228	Cytotoxic T-lymphocyte associated protein 4.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.890