Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
OTOGOtogelin. (2885 aa)    
Predicted Functional Partners:
STRC
Stereocilin.
    
 0.896
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13.
    
  0.831
GP1BB
Glycoprotein Ib platelet subunit beta.
    
 0.789
CEACAM16
Carcinoembryonic antigen related cell adhesion molecule 16.
   
 0.781
BRICD5
BRICHOS domain containing 5.
      
 0.761
ZPLD1
Zona pellucida like domain containing 1.
      
 0.727
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
    
  0.721
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
  0.721
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.705
SPARCL1
SPARC like 1.
   
 
 0.690
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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