Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TRPM5Transient receptor potential cation channel subfamily M member 5. (1160 aa)    
Predicted Functional Partners:
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.927
TAS1R3
Taste 1 receptor member 3.
      
 0.923
DCLK1
Doublecortin like kinase 1.
   
  
 0.914
CALHM1
Calcium homeostasis modulator 1.
      
 0.899
POU2F3
POU domain protein.
    
 
 0.893
GNAT3
G protein subunit alpha transducin 3.
      
 0.873
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
      
 0.864
TAS1R2
Taste 1 receptor member 2.
      
 0.846
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
      
 0.846
TAS1R1
Taste 1 receptor member 1.
      
 0.843
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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