Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102180307Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)    
Predicted Functional Partners:
LOC102185882
Histone H3; Belongs to the histone H3 family.
   
 0.992
H3-4
Histone H3; Belongs to the histone H3 family.
   
 0.992
LOC102180554
Histone H3; Belongs to the histone H3 family.
   
 0.992
LOC106503499
Histone H3; Belongs to the histone H3 family.
   
 0.992
LOC102189503
Histone H3; Belongs to the histone H3 family.
   
 0.992
H2BU1
Histone H2B; Belongs to the histone H2B family.
   
 0.979
H2BC11
Histone H2B; Belongs to the histone H2B family.
   
 0.979
H2BC12
Histone H2B; Belongs to the histone H2B family.
   
 0.976
LOC102181912
Histone H2B; Belongs to the histone H2B family.
   
 0.976
LOC102179187
Histone H2B; Belongs to the histone H2B family.
   
 0.976
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.