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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAND1Heart and neural crest derivatives expressed 1. (219 aa)    
Predicted Functional Partners:
ZIM2
Uncharacterized protein.
   
 
 0.751
BTG1
B-cell translocation protein 1.
      
 0.741
RNMT
mRNA cap guanine-N7 methyltransferase.
      
 0.731
NKX2-5
NK2 homeobox 5.
   
 
 0.574
GATA6
GATA binding protein 6.
   
 0.554
TCF4
Transcription factor 4.
   
 0.551
TCF3
Transcription factor 3.
   
 0.550
OTX1
Orthodenticle homeobox 1.
      
 0.531
NKX1-2
NK1 homeobox 2.
      
 0.512
GCM1
Glial cells missing transcription factor 1.
   
  
 0.496
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.