Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HAND1Heart and neural crest derivatives expressed 1. (219 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
    
 0.794
TCF3
Transcription factor 3.
    
 0.727
GATA6
GATA binding protein 6.
   
 0.670
GATA4
GATA binding protein 4.
   
 0.620
HAND2
Heart and neural crest derivatives expressed 2.
   
   0.620
FOXP4
Forkhead box P4.
      
 0.588
TCF4
Transcription factor 4.
    
 0.560
GCM1
Glial cells missing transcription factor 1.
   
  
 0.523
MESP1
Mesoderm posterior bHLH transcription factor 1.
     
 0.519
GATA5
GATA binding protein 5.
   
 0.508
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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