Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SH3KBP1SH3 domain-containing protein. (463 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.997
CBLB
Cbl proto-oncogene B.
    
 0.994
EGFR
Receptor protein-tyrosine kinase.
    
 0.992
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
   
 0.980
SH3GLB2
SH3 domain containing GRB2 like, endophilin B2.
    
 0.960
GRB2
Growth factor receptor bound protein 2.
    
 0.959
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.
    
 
 0.954
CBLC
Cbl proto-oncogene C.
    
 0.946
CD2AP
CD2 associated protein.
   
 
0.944
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.
   
 
 0.942
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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