Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PNKDPNKD metallo-beta-lactamase domain containing. (385 aa)    
Predicted Functional Partners:
PRRT2
Proline rich transmembrane protein 2.
    
 
 0.872
SUOX
Sulfite oxidase.
   
 
 0.804
TMEM208
Transmembrane protein 208.
      
 0.718
FBXL8
F-box domain-containing protein.
   
  
 0.695
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
      
 0.637
LOC108635042
Uncharacterized protein.
   
 
 0.619
PET117
PET117 cytochrome c oxidase chaperone.
     
 0.607
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.592
CACNG7
Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    
 0.587
TMEM91
Transmembrane protein 91.
      
 0.586
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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