XK protein (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

XK

XK-related protein. (444 aa)

Predicted Functional Partners:

NCF1

0.902

CYBA

0.899

NCF2

0.873

NCF4

0.866

RAC2

0.841

NOX4

0.795

MAPK14

0.789

MAPK12

0.789

MAPK13

0.789

MAPK1

0.787

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYBA	MAPK1	ENSCHIP00000012752	ENSCHIP00000000204	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.924
CYBA	MAPK12	ENSCHIP00000012752	ENSCHIP00000016029	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Mitogen-activated protein kinase 12.	0.885
CYBA	MAPK13	ENSCHIP00000012752	ENSCHIP00000027806	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Mitogen-activated protein kinase.	0.898
CYBA	MAPK14	ENSCHIP00000012752	ENSCHIP00000000781	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Mitogen-activated protein kinase.	0.903
CYBA	NCF1	ENSCHIP00000012752	ENSCHIP00000025402	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 1.	0.998
CYBA	NCF2	ENSCHIP00000012752	ENSCHIP00000030281	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 2.	0.994
CYBA	NCF4	ENSCHIP00000012752	ENSCHIP00000009913	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 4.	0.998
CYBA	NOX4	ENSCHIP00000012752	ENSCHIP00000024501	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 4.	0.995
CYBA	RAC2	ENSCHIP00000012752	ENSCHIP00000029928	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Rac family small GTPase 2.	0.990
CYBA	XK	ENSCHIP00000012752	ENSCHIP00000001550	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	XK-related protein.	0.899
MAPK1	CYBA	ENSCHIP00000000204	ENSCHIP00000012752	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.924
MAPK1	MAPK12	ENSCHIP00000000204	ENSCHIP00000016029	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase 12.	0.919
MAPK1	MAPK13	ENSCHIP00000000204	ENSCHIP00000027806	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.937
MAPK1	MAPK14	ENSCHIP00000000204	ENSCHIP00000000781	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.958
MAPK1	NCF1	ENSCHIP00000000204	ENSCHIP00000025402	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Neutrophil cytosolic factor 1.	0.943
MAPK1	NCF2	ENSCHIP00000000204	ENSCHIP00000030281	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Neutrophil cytosolic factor 2.	0.922
MAPK1	NCF4	ENSCHIP00000000204	ENSCHIP00000009913	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Neutrophil cytosolic factor 4.	0.932
MAPK1	RAC2	ENSCHIP00000000204	ENSCHIP00000029928	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Rac family small GTPase 2.	0.937
MAPK1	XK	ENSCHIP00000000204	ENSCHIP00000001550	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	XK-related protein.	0.787
MAPK12	CYBA	ENSCHIP00000016029	ENSCHIP00000012752	Mitogen-activated protein kinase 12.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.885