Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD59UPAR/Ly6 domain-containing protein. (122 aa)    
Predicted Functional Partners:
CD55
Uncharacterized protein.
     
 0.970
LOC102169209
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
   
 
 0.888
C9
Complement C9.
    
 0.848
LOC102175466
C-type lectin domain-containing protein.
     
 0.814
C1S
Complement C1s; Belongs to the peptidase S1 family.
     
 0.753
C1R
Complement C1r; Belongs to the peptidase S1 family.
     
 0.752
CLUL1
Clusterin; Belongs to the clusterin family.
      
 0.749
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
      
 0.736
C5
Complement C5.
    
 0.734
MBL2
Mannose binding lectin 2.
     
 0.722
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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