Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (233 aa)    
Predicted Functional Partners:
ACBD3
Acyl-CoA binding domain containing 3.
   
  
 0.854
CSTF1
Cleavage stimulation factor subunit 1.
      
 0.736
VAPA
VAMP associated protein A.
   
 0.726
RAB33B
RAB33B, member RAS oncogene family.
   
  
 0.713
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
    
  0.710
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
      
 0.694
ENSCHIP00000007836
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.651
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.651
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.646
NME8
NME/NM23 family member 8.
  
 0.640
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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