close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM54Transmembrane protein 54. (226 aa)    
Predicted Functional Partners:
SERF2
Small EDRK-rich factor 2; Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity). Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (By similarity).
      
 0.743
ZNF518B
Zinc finger protein 518B.
    
 0.723
TSPYL5
TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.706
TMEM126B
Transmembrane protein 126B.
      
 0.700
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.694
TMEM134
Transmembrane protein 134.
      
 0.693
SLC16A5
Solute carrier family 16 member 5.
    
 
 0.664
LYG1
Lysozyme g1.
      
 0.659
TRIM26
Tripartite motif containing 26.
    
 
 0.592
RPL12
Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.569
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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