Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (301 aa)    
Predicted Functional Partners:
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.965
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.940
SQLE
Squalene epoxidase.
   
 0.926
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 0.915
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.880
STYX
Serine/threonine/tyrosine interacting protein.
      
 0.878
CYP7B1
Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 0.869
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 0.866
CYP39A1
Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.825
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.825
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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