Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)    
Predicted Functional Partners:
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
      
 0.915
OLFM4
Olfactomedin 4.
      
 0.912
LRIG1
Leucine rich repeats and immunoglobulin like domains 1.
   
  
 0.838
AXIN2
Axin 2.
      
 0.832
CHGA
Chromogranin A.
      
 0.799
TCF3
Transcription factor 3.
   
 0.787
TCF4
Transcription factor 4.
   
 0.758
TCF12
Transcription factor 12.
   
 0.734
HOPX
Homeobox domain-containing protein.
    
 0.707
ID4
Inhibitor of DNA binding 4, HLH protein.
    
 0.694
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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