Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NEK10NIMA related kinase 10. (1163 aa)    
Predicted Functional Partners:
MCC
MCC regulator of WNT signaling pathway.
   
 
 0.691
PXYLP1
2-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family.
      
 0.603
TM9SF1
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
    
 0.600
TSC22D2
TSC22 domain family member 2.
    
 0.595
AP5M1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 
 0.595
NWD2
NACHT and WD repeat domain containing 2.
   
 0.584
TRAF7
TNF receptor associated factor 7.
   
 0.584
SCML4
Scm polycomb group protein like 4.
     
 0.581
BRAP
BRCA1 associated protein.
    
 0.581
CARMIL1
Capping protein regulator and myosin 1 linker 1.
      
 0.568
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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