FANCA protein (Capra hircus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

FANCA

FA complementation group A. (1416 aa)

Predicted Functional Partners:

FANCF

0.999

FANCM

0.999

FANCB

0.999

FAAP100

0.999

FAAP24

0.999

FANCG

0.999

FANCC

0.999

FANCI

0.998

FANCD2

0.998

FANCL

0.997

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAAP100	FAAP24	ENSCHIP00000020356	ENSCHIP00000023626	FA core complex associated protein 100.	FA core complex associated protein 24.	0.999
FAAP100	FANCA	ENSCHIP00000020356	ENSCHIP00000001913	FA core complex associated protein 100.	FA complementation group A.	0.999
FAAP100	FANCB	ENSCHIP00000020356	ENSCHIP00000014817	FA core complex associated protein 100.	Uncharacterized protein.	0.999
FAAP100	FANCC	ENSCHIP00000020356	ENSCHIP00000024710	FA core complex associated protein 100.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.999
FAAP100	FANCD2	ENSCHIP00000020356	ENSCHIP00000032582	FA core complex associated protein 100.	FA complementation group D2.	0.996
FAAP100	FANCF	ENSCHIP00000020356	ENSCHIP00000003311	FA core complex associated protein 100.	FA complementation group F.	0.999
FAAP100	FANCG	ENSCHIP00000020356	ENSCHIP00000024561	FA core complex associated protein 100.	FA complementation group G.	0.999
FAAP100	FANCI	ENSCHIP00000020356	ENSCHIP00000001071	FA core complex associated protein 100.	FA complementation group I.	0.996
FAAP100	FANCL	ENSCHIP00000020356	ENSCHIP00000020403	FA core complex associated protein 100.	RING-type domain-containing protein.	0.995
FAAP100	FANCM	ENSCHIP00000020356	ENSCHIP00000013958	FA core complex associated protein 100.	FA complementation group M.	0.999
FAAP24	FAAP100	ENSCHIP00000023626	ENSCHIP00000020356	FA core complex associated protein 24.	FA core complex associated protein 100.	0.999
FAAP24	FANCA	ENSCHIP00000023626	ENSCHIP00000001913	FA core complex associated protein 24.	FA complementation group A.	0.999
FAAP24	FANCB	ENSCHIP00000023626	ENSCHIP00000014817	FA core complex associated protein 24.	Uncharacterized protein.	0.999
FAAP24	FANCC	ENSCHIP00000023626	ENSCHIP00000024710	FA core complex associated protein 24.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.999
FAAP24	FANCD2	ENSCHIP00000023626	ENSCHIP00000032582	FA core complex associated protein 24.	FA complementation group D2.	0.995
FAAP24	FANCF	ENSCHIP00000023626	ENSCHIP00000003311	FA core complex associated protein 24.	FA complementation group F.	0.999
FAAP24	FANCG	ENSCHIP00000023626	ENSCHIP00000024561	FA core complex associated protein 24.	FA complementation group G.	0.999
FAAP24	FANCI	ENSCHIP00000023626	ENSCHIP00000001071	FA core complex associated protein 24.	FA complementation group I.	0.995
FAAP24	FANCL	ENSCHIP00000023626	ENSCHIP00000020403	FA core complex associated protein 24.	RING-type domain-containing protein.	0.996
FAAP24	FANCM	ENSCHIP00000023626	ENSCHIP00000013958	FA core complex associated protein 24.	FA complementation group M.	0.999