Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.983
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.970
ENO2
Uncharacterized protein.
     
 0.964
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
     
 0.963
ACSS2
Acyl-CoA synthetase short chain family member 2.
   
 
 0.955
PCK2
Phosphoenolpyruvate carboxykinase 2, mitochondrial.
   
  0.947
ENO3
Enolase 3.
     
 0.946
GOT1
Aspartate aminotransferase.
     
 0.946
GOT2
Aspartate aminotransferase.
     
 0.945
MDH2
Malate dehydrogenase.
     
 0.942
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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