Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHIP00000001945annotation not available (136 aa)    
Predicted Functional Partners:
ENSCHIP00000004308
annotation not available
   
 0.955
H2AX
Histone H2A; Belongs to the histone H2A family.
   
 0.949
LOC102180307
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.947
ENSCHIP00000004152
annotation not available
   
 0.947
ENSCHIP00000005277
annotation not available
   
 0.947
LOC102172954
Histone H4.
   
 0.947
ENSCHIP00000005753
annotation not available
   
 0.947
LOC106503502
Histone H4.
   
 0.947
LOC108636047
Histone H4.
   
 0.947
LOC106503503
Histone H4.
   
 0.947
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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