Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.789
USP31
Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family.
   
 0.716
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.698
TRMT10A
tRNA methyltransferase 10A.
   
  
 0.676
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.667
C3H1orf226
PID domain-containing protein.
    
 0.613
RAPGEF6
Uncharacterized protein.
    
 0.600
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.600
AFDN
Afadin, adherens junction formation factor.
    
 0.591
DENND5B
DENN domain containing 5B.
   
 
 0.585
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.