RAB4B protein (Capra hircus) - STRING interaction network

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Score

RAB4B

Uncharacterized protein. (213 aa)

Predicted Functional Partners:

RBSN

0.953

RUFY1

0.874

RUFY2

0.779

TBC1D16

0.744

RABEP1

0.709

HGS

0.667

STAM

0.644

CHML

0.641

RAB7A

0.629

RUFY3

0.595

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHML	RAB4B	ENSCHIP00000001148	ENSCHIP00000001965	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.641
CHML	RAB7A	ENSCHIP00000001148	ENSCHIP00000001040	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.951
HGS	RAB4B	ENSCHIP00000030557	ENSCHIP00000001965	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Uncharacterized protein.	0.667
HGS	RAB7A	ENSCHIP00000030557	ENSCHIP00000001040	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Uncharacterized protein.	0.415
HGS	RBSN	ENSCHIP00000030557	ENSCHIP00000020841	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Rabenosyn, RAB effector.	0.877
HGS	STAM	ENSCHIP00000030557	ENSCHIP00000002156	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.998
RAB4B	CHML	ENSCHIP00000001965	ENSCHIP00000001148	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.641
RAB4B	HGS	ENSCHIP00000001965	ENSCHIP00000030557	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.667
RAB4B	RAB7A	ENSCHIP00000001965	ENSCHIP00000001040	Uncharacterized protein.	Uncharacterized protein.	0.629
RAB4B	RABEP1	ENSCHIP00000001965	ENSCHIP00000020339	Uncharacterized protein.	Rabaptin, RAB GTPase binding effector protein 1.	0.709
RAB4B	RBSN	ENSCHIP00000001965	ENSCHIP00000020841	Uncharacterized protein.	Rabenosyn, RAB effector.	0.953
RAB4B	RUFY1	ENSCHIP00000001965	ENSCHIP00000030760	Uncharacterized protein.	RUN and FYVE domain containing 1.	0.874
RAB4B	RUFY2	ENSCHIP00000001965	ENSCHIP00000006604	Uncharacterized protein.	RUN and FYVE domain containing 2.	0.779
RAB4B	RUFY3	ENSCHIP00000001965	ENSCHIP00000002159	Uncharacterized protein.	RUN and FYVE domain containing 3.	0.595
RAB4B	STAM	ENSCHIP00000001965	ENSCHIP00000002156	Uncharacterized protein.	Signal transducing adaptor molecule.	0.644
RAB4B	TBC1D16	ENSCHIP00000001965	ENSCHIP00000010240	Uncharacterized protein.	TBC1 domain family member 16.	0.744
RAB7A	CHML	ENSCHIP00000001040	ENSCHIP00000001148	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.951
RAB7A	HGS	ENSCHIP00000001040	ENSCHIP00000030557	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.415
RAB7A	RAB4B	ENSCHIP00000001040	ENSCHIP00000001965	Uncharacterized protein.	Uncharacterized protein.	0.629
RABEP1	RAB4B	ENSCHIP00000020339	ENSCHIP00000001965	Rabaptin, RAB GTPase binding effector protein 1.	Uncharacterized protein.	0.709