Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)    
Predicted Functional Partners:
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
   
 0.996
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
   
 0.992
HSPE1
Uncharacterized protein; Belongs to the GroES chaperonin family.
 
 
 0.988
ENSCHIP00000021369
Uncharacterized protein; Belongs to the GroES chaperonin family.
  
 
 0.982
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.980
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 0.972
HSPA1L
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
   
 0.969
TLR4
TIR domain-containing protein; Belongs to the Toll-like receptor family.
    
 0.968
HSPA2
Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...]
   
 0.962
HSPA5
Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family.
   
 0.957
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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