Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
TUT1RRM domain-containing protein. (871 aa)    
Predicted Functional Partners:
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
   
 
 0.938
PRPF31
Pre-mRNA processing factor 31.
    
 
 0.934
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.917
PAPOLG
Poly(A) polymerase gamma.
   
 
 0.878
ENSCHIP00000005232
Lactamase_B domain-containing protein.
    
 0.866
CPSF3
Cleavage and polyadenylation specific factor 3.
    
 0.866
DIS3L2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]
    
 
 0.848
SYMPK
Symplekin.
   
 0.846
CCDC84
Coiled-coil domain containing 84.
    
   0.833
PRPF3
Pre-mRNA processing factor 3.
    
   0.829
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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