Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL10A1Collagen type X alpha 1 chain. (674 aa)    
Predicted Functional Partners:
MMP13
Matrix metallopeptidase 13.
   
 0.927
RUNX2
RUNX family transcription factor 2.
    
 0.915
COL4A6
Collagen IV NC1 domain-containing protein.
 
  
  0.884
ACAN
Aggrecan.
   
 0.881
SOX9
SRY-box transcription factor 9.
    
 
 0.845
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.799
PTHLH
Parathyroid hormone-like protein.
     
 0.754
SP7
Sp7 transcription factor.
    
 0.745
COMP
Cartilage oligomeric matrix protein.
   
 0.722
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5.
    
 0.715
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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