Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND1BDENN domain containing 1B. (780 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
    
 0.942
DENND1A
DENN domain containing 1A.
     
 0.824
RAB21
RAB21, member RAS oncogene family.
      
 0.768
TBC1D20
TBC1 domain family member 20.
      
 0.718
RAB17
RAB17, member RAS oncogene family.
      
 0.677
RAB22A
RAB22A, member RAS oncogene family.
      
 0.636
RAB13
Uncharacterized protein.
     
 0.623
SERPINA12
Serpin family A member 12; Belongs to the serpin family.
    
   0.580
PRAM1
PML-RARA regulated adaptor molecule 1.
   
  
 0.563
AVL9
AVL9 cell migration associated.
      
 0.550
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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