STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF6PHD finger protein 6. (366 aa)    
Predicted Functional Partners:
ASXL1
ASXL transcriptional regulator 1.
   
 0.749
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.740
SETBP1
SET binding protein 1.
   
 
 0.736
RBBP4
WD_REPEATS_REGION domain-containing protein.
   
 0.731
RBBP4-2
WD_REPEATS_REGION domain-containing protein.
   
 0.730
ZRSR2
Uncharacterized protein.
    
 
 0.716
BCORL1
BCL6 corepressor like 1.
    
 0.688
PHF1
PHD finger protein 1.
   
 0.681
U2AF1
Uncharacterized protein.
    
 
 0.678
ETV6
ETS variant 6.
    
 
 0.668
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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