STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF1Rap guanine nucleotide exchange factor 1. (1077 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.994
CRK
CRK proto-oncogene, adaptor protein.
    
 0.966
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.948
GRB2
Growth factor receptor bound protein 2.
   
 0.914
RAP1B
Ras-related protein Rap-1B.
    
 0.815
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.765
CBL
Cbl proto-oncogene.
    
 0.760
ATXN7L3B
Ataxin 7 like 3B.
      
 0.744
GAB1
GRB2 associated binding protein 1.
    
 0.740
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.699
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.