Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yaaAPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73117.1); Blastp hit to AAC73117.1 (258 aa), 86% identity in aa 1 - 257; Belongs to the UPF0246 family. (257 aa)    
Predicted Functional Partners:
yafJ
Similar to E. coli putative amidotransferase (AAC73327.1); Blastp hit to AAC73327.1 (255 aa), 93% identity in aa 1 - 255.
      
 0.852
yeaN
Similar to E. coli putative amino acid/amine transport protein (AAC74861.1); Blastp hit to AAC74861.1 (393 aa), 81% identity in aa 1 - 392.
  
    0.828
STM2486
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75528.1); Blastp hit to AAC75528.1 (287 aa), 92% identity in aa 1 - 286.
      
 0.751
ybgL
Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
      
 0.728
rarD
Chloramphenicol resistance; Similar to E. coli orf, hypothetical protein (AAC76822.1); Blastp hit to AAC76822.1 (300 aa), 83% identity in aa 8 - 297.
      
 0.714
yaaJ
AGCS family; similar to E. coli inner membrane transport protein (AAC73118.1); Blastp hit to AAC73118.1 (476 aa), 76% identity in aa 1 - 476.
  
    0.631
nxiA
Putative nickel transporter; Efflux system for nickel and cobalt.
 
      0.556
grxA
Redox coenzyme for glutathione-dependent ribonucleotide reductase glutaredoxin1; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity); Belongs to the glutaredoxin family.
 
   
 0.528
yqcD
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
 
   
 0.514
mnmC
Putative peptidase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.
 
     0.455
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.