Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yaaIPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73124.1); Blastp hit to AAC73124.1 (134 aa), 81% identity in aa 1 - 134; Belongs to the UPF0412 family. (134 aa)    
Predicted Functional Partners:
STM3411
Putative cytoplasmic protein.
      
 0.858
yaeJ
putative-tRNA hydrolase domain protein; Similar to E. coli orf, hypothetical protein (AAC73302.1); Blastp hit to AAC73302.1 (140 aa), 85% identity in aa 1 - 136.
      
 0.855
htgA
Functions on sigma 32 promoters permitting growth at high temperature; similar to E. coli putative oxidoreductase (AAC73122.1); Blastp hit to AAC73122.1 (237 aa), 87% identity in aa 1 - 236.
  
  
 0.757
rpmE2
Putative 50S ribosomal protein L31 (second copy); Similar to E. coli putative ribosomal protein (AAC73399.1); Blastp hit to AAC73399.1 (87 aa), 74% identity in aa 1 - 86.
   
  
 0.757
rplX
50S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
      
 0.579
rplR
50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
      
 0.514
rplW
50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
      
 0.513
yaaH
Putative regulatory protein; Similar to E. coli orf, hypothetical protein (AAC73121.1); Blastp hit to AAC73121.1 (188 aa), 90% identity in aa 1 - 188.
  
  
 0.474
rpmJ
Similar to E. coli 50S ribosomal subunit protein L36 (AAC76324.1); Blastp hit to AAC76324.1 (38 aa), 100% identity in aa 1 - 38; Belongs to the bacterial ribosomal protein bL36 family.
      
 0.464
rpmJ2
Putative 50S ribosomal protein L36 (second copy); Belongs to the bacterial ribosomal protein bL36 family.
      
 0.451
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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