Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM0035Similar to E. coli putative sulfatase (AAC76701.1); Blastp hit to AAC76701.1 (497 aa), 26% identity in aa 2 - 420. (497 aa)    
Predicted Functional Partners:
nanH
Sialidase; Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections.
  
 
  0.957
STM3122
Similar to E. coli putative sulfatase (AAC74571.1); Blastp hit to AAC74571.1 (571 aa), 27% identity in aa 120 - 327, 43% identity in aa 322 - 358, 37% identity in aa 44 - 86, 31% identity in aa 435 - 471.
  
 
 
0.928
melA
Alpha-galactosidase. (SW:AGAL_SALTY); Belongs to the glycosyl hydrolase 4 family.
   
 
  0.900
STM0036
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 46% identity in aa 8 - 401.
 
    0.887
STM1287
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 46% identity in aa 10 - 401.
 
     0.740
STM3966
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 47% identity in aa 11 - 402.
 
    0.738
yidF
Putative cytoplasmic protein; Similar to E. coli putative transcriptional regulator (AAC76697.1); Blastp hit to AAC76697.1 (165 aa), 48% identity in aa 1 - 165.
 
     0.736
STM3123
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 36% identity in aa 4 - 248, 34% identity in aa 230 - 387.
 
    0.722
STM0037
Putative cytoplasmic protein.
  
    0.646
STM3082
Putative zinc-binding dehydrogenase; Similar to E. coli putative oxidoreductase (AAC77314.1); Blastp hit to AAC77314.1 (345 aa), 54% identity in aa 9 - 345.
  
    0.434
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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