Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM0038Putative arylsulfatase. (571 aa)    
Predicted Functional Partners:
tdcE
Pyruvate formate-lyase 4; Similar to E. coli probable formate acetyltransferase 3 (AAC76149.1); Blastp hit to AAC76149.1 (746 aa), 93% identity in aa 1 - 741; 2-ketobutyrate formate-lyase.
      
 0.751
dinI
DNA damage-inducible protein I; Inhibits UmuD processing; similar to E. coli damage-inducible protein I (AAC74145.1); Blastp hit to AAC74145.1 (81 aa), 85% identity in aa 1 - 81.
      
 0.749
STM0037
Putative cytoplasmic protein.
  
    0.667
aceF
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
      
 0.612
nhaA
NhaA family of transport protein, Na+/H antiporter, pH dependent; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
       0.601
nhaR
LysR family; similar to E. coli transcriptional activator of nhaA (AAC73131.1); Blastp hit to AAC73131.1 (301 aa), 92% identity in aa 1 - 296; Belongs to the LysR transcriptional regulatory family.
 
     0.541
STM0036
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 46% identity in aa 8 - 401.
  
    0.504
stfD
Periplasmic fimbrial chaperone StfD (gi|3747031).
      
 0.451
STM0035
Similar to E. coli putative sulfatase (AAC76701.1); Blastp hit to AAC76701.1 (497 aa), 26% identity in aa 2 - 420.
  
    0.426
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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