STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM0052Putative transcription regulator sensor for citrate; Similar to E. coli sequence similarity to Shigella regulator (AAC73721.1); Blastp hit to AAC73721.1 (226 aa), 47% identity in aa 5 - 223. (228 aa)    
Predicted Functional Partners:
STM0053
Putative transcription regulator; Histidine kinase for citrate; similar to E. coli putative sensor-type protein (AAC73720.1); Blastp hit to AAC73720.1 (552 aa), 42% identity in aa 12 - 538.
 0.996
dpiB
Sensory histidine kinase in two-component regulatory system with DpiA; Regulation of cit operon and plasmid inheritance genes; similar to E. coli putative sensor-type protein (AAC73720.1); Blastp hit to AAC73720.1 (552 aa), 86% identity in aa 2 - 552.
 0.986
dpiA
Response regulator in two-component regulatory system with DpiB; Transcriptional regulation of cit operon (citrate fermentation) genes and of plasmid inheritance genes (OmpR family); similar to E. coli sequence similarity to Shigella regulator (AAC73721.1); Blastp hit to AAC73721.1 (226 aa), 84% identity in aa 1 - 226.
  
  
 
0.906
dcuS
Sensory histidine kinase in two-component retgulatory system with DcuR; Senses fumarate/C4-dicarboxylate; similar to E. coli putative 2-component sensor protein (AAC77086.1); Blastp hit to AAC77086.1 (543 aa), 81% identity in aa 1 - 542.
 
 0.868
citG2
Putative modifier of citrate lyase protein; Similar to E. coli orf, hypothetical protein (AAC73714.1); Blastp hit to AAC73714.1 (292 aa), 47% identity in aa 1 - 290.
     
 0.809
STM3350
Putative inner membrane protein.
     
 0.742
yieF
Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76736.1); Blastp hit to AAC76736.1 (188 aa), 92% identity in aa 1 - 187.
      
 0.670
citP
Putative citrate-sodium symport; Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system); Belongs to the sodium:citrate (SCF) symporter family.
 
    0.633
citC
Citrate lyase synthetase (citrate (pro-3S)-lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
      
 0.616
citC2
Putative citrate lyase synthetase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
     
 0.560
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.