close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citPPutative citrate-sodium symport; Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system); Belongs to the sodium:citrate (SCF) symporter family. (446 aa)    
Predicted Functional Partners:
citX
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73715.1); Blastp hit to AAC73715.1 (183 aa), 75% identity in aa 1 - 179.
 
   
 0.929
citD
Citrate lyase acyl carrier protein (gamma chain); Covalent carrier of the coenzyme of citrate lyase.
 
   
 0.926
oadA1
Putative oxalacetate decarboxylase, subunit alpha; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
  
  
 0.850
citT
DASS family, citrate:succinate transport (antiport) protein; Similar to E. coli putative a membrane protein (AAC73713.1); Blastp hit to AAC73713.1 (487 aa), 94% identity in aa 1 - 487.
   
  
 0.838
citE
Similar to E. coli citrate lyase beta chain (acyl lyase subunit) (AAC73717.1); Blastp hit to AAC73717.1 (307 aa), 95% identity in aa 6 - 307; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.783
oadG
Oxaloacetate decarboxylase gamma chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
 
   
 0.763
citC2
Putative citrate lyase synthetase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
  
 0.717
oadB
Oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
     
 0.714
STM0053
Putative transcription regulator; Histidine kinase for citrate; similar to E. coli putative sensor-type protein (AAC73720.1); Blastp hit to AAC73720.1 (552 aa), 42% identity in aa 12 - 538.
 
  
 0.712
oadA
Putative sodium ion pump; oxaloacetate decarboxylase alpha chain. (SW:DCOA_SALTY).
     
 0.711
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.