| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM1128 | caiT | STM1128 | STM0074 | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Putative BCCT family betaine/carnitine/choline transport protein; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | 0.545 |
| caiA | caiB | STM0073 | STM0072 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | 0.994 |
| caiA | caiC | STM0073 | STM0071 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.983 |
| caiA | caiD | STM0073 | STM0070 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.996 |
| caiA | caiE | STM0073 | STM0069 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Stimulates carnitine racemase activity of CaiD and CaiB activity; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.932 |
| caiA | caiT | STM0073 | STM0074 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Putative BCCT family betaine/carnitine/choline transport protein; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | 0.989 |
| caiA | fixA | STM0073 | STM0075 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Putative flavoprotein reductase, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA. | 0.944 |
| caiA | fixB | STM0073 | STM0076 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Putative electron transfer flavoprotein, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA. | 0.993 |
| caiA | fixC | STM0073 | STM0077 | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Related to carnitine metabolism protein; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family. | 0.923 |
| caiB | caiA | STM0072 | STM0073 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.994 |
| caiB | caiC | STM0072 | STM0071 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.980 |
| caiB | caiD | STM0072 | STM0070 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.982 |
| caiB | caiE | STM0072 | STM0069 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Stimulates carnitine racemase activity of CaiD and CaiB activity; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.922 |
| caiB | caiT | STM0072 | STM0074 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Putative BCCT family betaine/carnitine/choline transport protein; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | 0.953 |
| caiB | fixA | STM0072 | STM0075 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Putative flavoprotein reductase, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA. | 0.854 |
| caiB | fixB | STM0072 | STM0076 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Putative electron transfer flavoprotein, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA. | 0.854 |
| caiB | fixC | STM0072 | STM0077 | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | Related to carnitine metabolism protein; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family. | 0.902 |
| caiC | caiA | STM0071 | STM0073 | crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.983 |
| caiC | caiB | STM0071 | STM0072 | crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily. | 0.980 |
| caiC | caiD | STM0071 | STM0070 | crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. | 0.975 |
