STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixAPutative flavoprotein reductase, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (256 aa)    
Predicted Functional Partners:
fixB
Putative electron transfer flavoprotein, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 0.998
fixX
Putative ferredoxin; Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster-containing protein (By similarity).
 
 0.977
fixC
Related to carnitine metabolism protein; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family.
 
 
 0.971
STM0856
Putative electron transfer flavoprotein alpha subunit; Similar to E. coli putative flavoprotein (AAC74768.1); Blastp hit to AAC74768.1 (312 aa), 35% identity in aa 65 - 310.
 0.956
ydiR
Similar to E. coli putative flavoprotein (AAC74768.1); Blastp hit to AAC74768.1 (312 aa), 72% identity in aa 1 - 312.
 
 0.947
caiA
Putative acyl-CoA dehydrogenase, carnitine metabolism; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family.
 
 
 0.944
STM0858
Putative dehydrogenase (flavoproteins); Accepts electrons from ETF and reduces ubiquinone.
 
 
 0.918
ydiO
Putative acyl-CoA dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74765.1); Blastp hit to AAC74765.1 (401 aa), 95% identity in aa 19 - 401.
 
 
 
 0.857
caiB
L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily.
 
  
 0.854
caiD
Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
 
 
 0.830
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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