STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
yabJPutative ABC-transport protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable). Is also involved in thiamine pyrophosphate (TPP) transport. Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (235 aa)    
Predicted Functional Partners:
yabK
Putative binding-protein-dependent transport system inner membrane component; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in thiamine pyrophosphate transport.
 
 
 0.999
tbpA
Thiamine-binding periplasmic protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Is also involved in thiamine pyrophosphate transport.
 
 
 0.992
yjgF
Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...]
      
 0.899
sapD
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the ABC transporter superfamily.
 
    
0.895
mdlB
Putative ABC superfamily (atp&membrane) transporter; Similar to E. coli putative ATP-binding component of a transport system (AAC73552.1); Blastp hit to AAC73552.1 (593 aa), 88% identity in aa 1 - 593.
 
   
0.872
oppD
Oligopeptide transport protein; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
 
    
0.870
dppD
Dipeptide transport protein; ABC superfamily (atp_bind); similar to E. coli putative ATP-binding component of dipeptide transport system (AAC76566.1); Blastp hit to AAC76566.1 (327 aa), 95% identity in aa 1 - 327; Belongs to the ABC transporter superfamily.
 
    
0.805
cysU
Thiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
 
     0.782
modB
Molybdate transporter; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
      0.771
yafB
2,5-diketo-D-gluconate reductase B; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
      
 0.746
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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