Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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yabKPutative binding-protein-dependent transport system inner membrane component; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in thiamine pyrophosphate transport. (536 aa)    
Predicted Functional Partners:
yabJ
Putative ABC-transport protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable). Is also involved in thiamine pyrophosphate (TPP) transport. Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
 
 
 0.998
tbpA
Thiamine-binding periplasmic protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Is also involved in thiamine pyrophosphate transport.
 
 
 0.996
phnS
2-aminoethylphosphonate transporter, periplasmic-binding component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import; Belongs to the bacterial solute-binding protein 1 family.
 
  
 0.708
pgtC
Protein for signal transmission; Required for PgtP expression, it may act jointly with the PgtA/PgtB signaling proteins.
  
  
 0.670
yohK
Putative transmembrane protein; Similar to E. coli putative seritonin transporter (AAC75203.1); Blastp hit to AAC75203.1 (231 aa), 90% identity in aa 1 - 230.
      
 0.643
yabN
Putative periplasmic binding protein of transport system; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
 
   
 0.622
phnT
2-aminoethylphosphonate transporter ATPase component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system.
  
 
 0.600
potG
Putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
  
 
 0.600
potA
Spermidine/putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
  
 
 0.600
thiL
Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
   
  
 0.593
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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