node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frdA | nadC | STM4343 | STM0145 | Fumarate reductase; Anaerobic; flavoprotein subunit; similar to E. coli fumarate reductase, anaerobic, flavoprotein subunit (AAC77114.1); Blastp hit to AAC77114.1 (602 aa), 95% identity in aa 1 - 595. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.933 |
nadA | nadB | STM0756 | STM2641 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.999 |
nadA | nadC | STM0756 | STM0145 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.999 |
nadA | nadD | STM0756 | STM0645 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Putative nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.923 |
nadA | nadE | STM0756 | STM1310 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.894 |
nadA | nadR | STM0756 | STM4580 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.969 |
nadA | pncA | STM0756 | STM1293 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | 0.820 |
nadA | pncB | STM0756 | STM1004 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP. | 0.957 |
nadB | nadA | STM2641 | STM0756 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
nadB | nadC | STM2641 | STM0145 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.999 |
nadB | nadD | STM2641 | STM0645 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Putative nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.932 |
nadB | nadE | STM2641 | STM1310 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.928 |
nadB | nadR | STM2641 | STM4580 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.965 |
nadB | pncA | STM2641 | STM1293 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | 0.910 |
nadB | pncB | STM2641 | STM1004 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP. | 0.962 |
nadC | frdA | STM0145 | STM4343 | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Fumarate reductase; Anaerobic; flavoprotein subunit; similar to E. coli fumarate reductase, anaerobic, flavoprotein subunit (AAC77114.1); Blastp hit to AAC77114.1 (602 aa), 95% identity in aa 1 - 595. | 0.933 |
nadC | nadA | STM0145 | STM0756 | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
nadC | nadB | STM0145 | STM2641 | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.999 |
nadC | nadD | STM0145 | STM0645 | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Putative nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.993 |
nadC | nadE | STM0145 | STM1310 | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.935 |