| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ampD | ampE | STM0146 | STM0147 | N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | 0.958 |
| ampD | ampG | STM0146 | STM0444 | N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | MFS family, muropeptide transporter; Similar to E. coli regulates beta-lactamase synthesis (AAC73536.1); Blastp hit to AAC73536.1 (491 aa), 91% identity in aa 1 - 490. | 0.963 |
| ampD | nadC | STM0146 | STM0145 | N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.722 |
| ampE | ampD | STM0147 | STM0146 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | 0.958 |
| ampE | ampG | STM0147 | STM0444 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | MFS family, muropeptide transporter; Similar to E. coli regulates beta-lactamase synthesis (AAC73536.1); Blastp hit to AAC73536.1 (491 aa), 91% identity in aa 1 - 490. | 0.766 |
| ampE | mdoC | STM0147 | STM1149 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | 0.735 |
| ampE | nadC | STM0147 | STM0145 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.794 |
| ampE | ycdY | STM0147 | STM1137 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Similar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184. | 0.728 |
| ampE | yeeA | STM0147 | STM2060 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352. | 0.749 |
| ampE | yhfC | STM0147 | STM3473 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Putative MFS family transport protein; Similar to E. coli putative transport (AAC76389.1); Blastp hit to AAC76389.1 (393 aa), 90% identity in aa 1 - 393. | 0.738 |
| ampE | yhfK | STM0147 | STM3467 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76383.1); Blastp hit to AAC76383.1 (696 aa), 86% identity in aa 1 - 695. | 0.758 |
| ampE | yihI | STM0147 | STM4003 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Putative cytoplasmic protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.670 |
| ampE | yraM | STM0147 | STM3264 | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | Putative transglycosylase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.672 |
| ampG | ampD | STM0444 | STM0146 | MFS family, muropeptide transporter; Similar to E. coli regulates beta-lactamase synthesis (AAC73536.1); Blastp hit to AAC73536.1 (491 aa), 91% identity in aa 1 - 490. | N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | 0.963 |
| ampG | ampE | STM0444 | STM0147 | MFS family, muropeptide transporter; Similar to E. coli regulates beta-lactamase synthesis (AAC73536.1); Blastp hit to AAC73536.1 (491 aa), 91% identity in aa 1 - 490. | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | 0.766 |
| mdoC | ampE | STM1149 | STM0147 | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. | 0.735 |
| mdoC | ycdY | STM1149 | STM1137 | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | Similar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184. | 0.565 |
| mdoC | yeeA | STM1149 | STM2060 | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352. | 0.459 |
| mdoC | yhfK | STM1149 | STM3467 | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76383.1); Blastp hit to AAC76383.1 (696 aa), 86% identity in aa 1 - 695. | 0.511 |
| mdoC | yihI | STM1149 | STM4003 | Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | Putative cytoplasmic protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.409 |