Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yacHSimilar to E. coli putative membrane protein (AAC73228.1); Blastp hit to AAC73228.1 (617 aa), 29% identity in aa 3 - 523. (540 aa)    
Predicted Functional Partners:
STM0156
Putative periplasmic protein.
 
  
 0.967
ybeU
Putative cytoplasmic protein; Similar to E. coli putative tRNA ligase (AAC73749.1); Blastp hit to AAC73749.1 (235 aa), 61% identity in aa 1 - 235.
  
 
 0.919
yobD
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74890.1); Blastp hit to AAC74890.1 (152 aa), 88% identity in aa 1 - 152.
      
 0.895
STM1228
Putative periplasmic protein.
      
 0.859
yeaL
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74859.1); Blastp hit to AAC74859.1 (148 aa), 94% identity in aa 1 - 130.
      
 0.853
STM2911
Putative permease; Similar to E. coli multidrug resistance; probably membrane translocase (AAC75733.1); Blastp hit to AAC75733.1 (512 aa), 29% identity in aa 15 - 201, 30% identity in aa 284 - 319.
   
  
 0.818
lpfD
Long polar fimbrial operon protein; LPFD protein precursor. (SW:LPFD_SALTY).
      
 0.783
ydeE
Similar to E. coli putative transport protein (AAC74607.1); Blastp hit to AAC74607.1 (395 aa), 76% identity in aa 1 - 395.
  
   
 0.752
yeiG
Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde.
      
 0.723
ybfE
LexA regulated, putative SOS response; Similar to E. coli orf, hypothetical protein (AAC73779.1); Blastp hit to AAC73779.1 (120 aa), 90% identity in aa 24 - 120.
      
 0.700
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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