Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yadFPutative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (220 aa)    
Predicted Functional Partners:
ychM
Putative SulP family transport protein; Similar to E. coli orf, hypothetical protein (AAC74290.1); Blastp hit to AAC74290.1 (550 aa), 93% identity in aa 1 - 550.
 
  
 0.842
yadH
Putative transport protein; ABC superfamily (membrane); similar to E. coli orf, hypothetical protein (AAC73239.1); Blastp hit to AAC73239.1 (256 aa), 94% identity in aa 1 - 256.
       0.625
focA
Formate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285.
  
    0.590
yfdC
Similar to E. coli putative transport (AAC75407.1); Blastp hit to AAC75407.1 (310 aa), 87% identity in aa 1 - 304.
  
    0.590
nirC
FNT family nitrite transport protein; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane; Belongs to the FNT transporter (TC 2.A.44) family.
  
    0.590
yadG
Putative ABC-type multidrug transport system, ATPase component; Similar to E. coli putative ATP-binding component of a transport system (AAC73238.1); Blastp hit to AAC73238.1 (308 aa), 95% identity in aa 1 - 308.
       0.580
caiE
Stimulates carnitine racemase activity of CaiD and CaiB activity; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family.
    
 
 0.575
yrdA
Putative ferripyochelin binding protein; Similar to E. coli putative transferase (AAC76304.1); Blastp hit to AAC76304.1 (256 aa), 87% identity in aa 73 - 256.
    
 
 0.575
gpt
Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.532
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.532
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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