STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
stiAPutative fimbrial subunit; Similar to E. coli major type 1 subunit fimbrin (pilin) (AAC77270.1); Blastp hit to AAC77270.1 (182 aa), 37% identity in aa 1 - 181. (179 aa)    
Predicted Functional Partners:
stiB
Putative fimbrial chaparone; Similar to E. coli periplasmic chaperone, required for type 1 fimbriae (AAC77272.1); Blastp hit to AAC77272.1 (241 aa), 39% identity in aa 20 - 235.
  
 
 0.985
stiC
Putative fimbrial usher; Similar to E. coli putative outer membrane protein (AAC76178.1); Blastp hit to AAC76178.1 (838 aa), 39% identity in aa 20 - 558, 34% identity in aa 493 - 837.
  
 
 0.964
stcA
Similar to E. coli putative fimbrial-like protein (AAC75172.1); Blastp hit to AAC75172.1 (180 aa), 33% identity in aa 1 - 180.
      
 0.931
stiH
Putative fimbriae; Lpfd protein precursor (SW:LPFD_SALTY).
     
 0.930
stbA
Putative fimbriae; Similar to E. coli major type 1 subunit fimbrin (pilin) (AAC77270.1); Blastp hit to AAC77270.1 (182 aa), 28% identity in aa 1 - 182.
   
  
 0.899
stdA
Similar to E. coli putative fimbrial-like protein (AAC73813.1); Blastp hit to AAC73813.1 (188 aa), 32% identity in aa 8 - 187.
      
 0.893
rrmA
23S rRNA m1G745 methyltransferase; Similar to E. coli putative enzyme (AAC74892.1); Blastp hit to AAC74892.1 (269 aa), 80% identity in aa 1 - 268.
   
  
 0.763
stfA
Major fimbrial subunit StfA (gi|3747029).
   
  
 0.690
yneJ
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74599.1); Blastp hit to AAC74599.1 (293 aa), 84% identity in aa 1 - 283; Belongs to the LysR transcriptional regulatory family.
      
 0.678
invE
Invasion protein; Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 TTSS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 TTSS effector proteins SipB, SipC and SipD and negatively influences the secretion of [...]
      
 0.576
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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