Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM0233Putative endochitinase. (587 aa)    
Predicted Functional Partners:
STM0018
Putative exochitinase.
 
 
 0.993
yaeL
Putative membrane-associated Zn-dependent protease; A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA. This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA (By similarity); Belongs to the peptidase M50B family.
     
 0.780
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      
 0.726
STM4309
Putative periplasmic or exported protein.
  
    0.697
iroB
Putative glycosyl transferase; Related to UDP-glucuronosyltransferase.
  
  
 0.691
ldcC
Similar to E. coli lysine decarboxylase 2, constitutive (AAC73297.1); Blastp hit to AAC73297.1 (713 aa), 91% identity in aa 1 - 712.
 
    0.634
STM4503
Putative inner membrane protein; Unknown (gi|5616505).
  
     0.601
STM2606
Gifsy-1 prophage protein; Similar to head-tail preconnector gp4 of phage 21.
  
     0.591
STM2603
Gifsy-1 prophage protein; Similar to head protein gp7 of phage 21.
  
     0.589
STM2608
Gifsy-1 prophage protein; Similar to terminase large chain gp2 of N15; similar to E. coli orf, hypothetical protein (AAC73662.1); Blastp hit to AAC73662.1 (247 aa), 53% identity in aa 7 - 132.
  
     0.571
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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