Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yaePPutative cytoplasmic protein; Belongs to the UPF0253 family. (72 aa)    
Predicted Functional Partners:
yccJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74088.1); Blastp hit to AAC74088.1 (75 aa), 92% identity in aa 1 - 75.
   
  
 0.897
ybfN
Putative lipoprotein; Similar to E. coli orf, hypothetical protein (AAC73776.1); Blastp hit to AAC73776.1 (108 aa), 84% identity in aa 1 - 107.
      
 0.895
rof
Modulator of Rho-dependent transcription termination; Similar to E. coli orf, hypothetical protein (AAC73300.1); Blastp hit to AAC73300.1 (86 aa), 81% identity in aa 1 - 86.
  
  
 0.869
yacC
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73233.1); Blastp hit to AAC73233.1 (156 aa), 95% identity in aa 42 - 156.
   
  
 0.851
yihE
Putative homoserine kinase type II; A protein kinase that (auto)phosphorylates on Ser and Thr residues, probably involved in the extracytoplasmic stress response. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species (By similarity).
   
  
 0.851
yaiE
Putative cytoplasmic protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
   
  
 0.727
ycbK
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74012.1); Blastp hit to AAC74012.1 (182 aa), 95% identity in aa 1 - 182.
      
 0.720
yaeQ
Putative cytoplasmic protein; Hypothetical 20.8 Kda protein in mesJ-cutF intergenic region. (SW:YAEQ_SALTY).
       0.517
yaeJ
putative-tRNA hydrolase domain protein; Similar to E. coli orf, hypothetical protein (AAC73302.1); Blastp hit to AAC73302.1 (140 aa), 85% identity in aa 1 - 136.
       0.517
iap
Similar to E. coli alkaline phosphatase isozyme conversion, aminopeptidase (AAC75795.1); Blastp hit to AAC75795.1 (345 aa), 85% identity in aa 1 - 344.
      
 0.450
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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