Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yafB2,5-diketo-D-gluconate reductase B; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). (267 aa)    
Predicted Functional Partners:
yafA
Putative hydrolase of the alpha/beta superfamily; Displays esterase activity toward pNP-butyrate.
   
 
 0.900
yabJ
Putative ABC-transport protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable). Is also involved in thiamine pyrophosphate (TPP) transport. Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
      
 0.695
yhdN
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76318.1); Blastp hit to AAC76318.1 (122 aa), 86% identity in aa 1 - 122.
      
 0.677
yeaG
Putative Ser protein kinase; Similar to E. coli orf, hypothetical protein (AAC74853.1); Blastp hit to AAC74853.1 (644 aa), 98% identity in aa 1 - 644.
   
    0.598
yqhE
2,5-diketo-D-gluconate reductase A; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
  
  
0.585
yqjD
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76133.1); Blastp hit to AAC76133.1 (101 aa), 90% identity in aa 1 - 101.
   
    0.583
ydiZ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74794.1); Blastp hit to AAC74794.1 (96 aa), 69% identity in aa 1 - 94.
   
    0.582
dgoK
Similar to E. coli 2-oxo-3-deoxygalactonate kinase (AAC76716.1); Blastp hit to AAC76716.1 (292 aa), 81% identity in aa 1 - 292.
   
  
 0.551
stbB
Putative fimbriae; Similar to E. coli probable pilin chaperone similar to PapD (AAC73251.1); Blastp hit to AAC73251.1 (246 aa), 40% identity in aa 1 - 240.
  
   
 0.545
yfbT
Similar to E. coli putative phosphatase (AAC75353.1); Blastp hit to AAC75353.1 (222 aa), 86% identity in aa 1 - 221.
      
 0.516
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.