STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yafSPutative SAM-dependent methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73318.1); Blastp hit to AAC73318.1 (246 aa), 86% identity in aa 7 - 244. (240 aa)    
Predicted Functional Partners:
yafE
Putative methyltransferase in menaquinone/biotin biosynthesis; Similar to E. coli putative biotin synthesis protein (AAC73315.1); Blastp hit to AAC73315.1 (207 aa), 71% identity in aa 3 - 206.
      
 0.937
yjhP
Similar to E. coli putative methyltransferase (AAC77262.1); Blastp hit to AAC77262.1 (248 aa), 30% identity in aa 1 - 138.
   
 
 0.927
yhiQ
Putative SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA.
 
  
 0.917
yecO
Putative SAM-dependent methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
     
 0.899
tehB
Putative methyltransferase; Tellurite resistance; similar to E. coli tellurite resistance (AAC74512.1); Blastp hit to AAC74512.1 (197 aa), 84% identity in aa 1 - 196.
  
  
 0.892
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
     
 0.872
yfcB
Putative methylase; Specifically methylates the 50S ribosomal protein L3 on 'Gln- 150'; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
 
   
 0.797
ydhL
Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125.
      
 0.763
rseB
Anti sigma E (sigma 24) factor, negative regulator; Similar to E. coli regulates activity of sigma-E factor (AAC75624.1); Blastp hit to AAC75624.1 (318 aa), 89% identity in aa 1 - 318.
  
     0.753
smtA
S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
   
 
 0.737
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (34%) [HD]