Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
STM0272Putative ATPase with chaperone activity; Homolog of Yersinia clpB; similar to E. coli ATP-binding component of serine protease (AAC73969.1); Blastp hit to AAC73969.1 (758 aa), 42% identity in aa 150 - 449, 40% identity in aa 421 - 685, 32% identity in aa 30 - 74; Belongs to the ClpA/ClpB family. (879 aa)    
Predicted Functional Partners:
STM0285
Putative inner membrane protein.
 
  
 0.994
STM0274
Putative cytoplasmic protein.
  
 0.993
STM0271
Putative cytoplasmic protein.
  
    0.984
STM3131
Putative cytoplasmic protein.
 
  
 0.965
dnaK
Chaperone Hsp70; Acts as a chaperone.
  
 
 0.952
STM4509
Putative cytoplasmic protein.
 
  
 0.951
STM0273
Putative cytoplasmic protein.
 
  
 0.945
STM1033
Gifsy-2 prophage Clp protease-like protein; Similar to E. coli ATP-dependent proteolytic subunit of clpA-clpP serine protease, heat shock protein F21.5 (AAC73540.1); Blastp hit to AAC73540.1 (207 aa), 29% identity in aa 73 - 203; Belongs to the peptidase S14 family.
   
 
 0.923
STM0266
Putative cytoplasmic protein.
 
  
 0.919
STM0291
Putative RHS-family protein; Similar to E. coli rhsD protein in rhs element (AAC73599.1); Blastp hit to AAC73599.1 (1426 aa), 27% identity in aa 315 - 985, 46% identity in aa 1151 - 1261, 25% identity in aa 297 - 788, 24% identity in aa 346 - 870, 22-1073758628dentity in aa 465 - 904, 26% identity in aa 317 - 724, 32-1073758654dentity in aa 4 - 143, 24% identity in aa 232 - 605, 21% identity in aa 562 - 970, 23% identity in aa 318 - 755, 32% identity in aa 974 - 1076, 26% identity in aa 935 - 1051, 22% identity in aa 358 - 540, 37% identity in aa 1 - 32, 31-1073758588dentity in aa 1041 [...]
 
  
 0.917
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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