| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysK | glyA | STM2430 | STM2555 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | 0.728 |
| cysK | gshA | STM2430 | STM2818 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Glutamate--cysteine ligase. (SW:GSH1_SALTY); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.815 |
| cysK | pepA | STM2430 | STM4477 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.812 |
| cysK | pepB | STM2430 | STM2536 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Putative aminopeptidase; Probably plays an important role in intracellular peptide degradation; Belongs to the peptidase M17 family. | 0.812 |
| cysK | pepD | STM2430 | STM0316 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Similar to E. coli aminoacyl-histidine dipeptidase (peptidase D) (AAC73341.1); Blastp hit to AAC73341.1 (485 aa), 92% identity in aa 1 - 485. | 0.831 |
| cysK | pepN | STM2430 | STM1057 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Similar to E. coli aminopeptidase N (AAC74018.1); Blastp hit to AAC74018.1 (870 aa), 94% identity in aa 1 - 870. | 0.832 |
| cysK | ybdK | STM2430 | STM0583 | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | Putative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. | 0.800 |
| ggt | gshA | STM3551 | STM2818 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Glutamate--cysteine ligase. (SW:GSH1_SALTY); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.912 |
| ggt | gshB | STM3551 | STM3095 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Similar to E. coli glutathione synthetase (AAC75984.1); Blastp hit to AAC75984.1 (316 aa), 90% identity in aa 1 - 313. | 0.943 |
| ggt | pepA | STM3551 | STM4477 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.946 |
| ggt | pepB | STM3551 | STM2536 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Putative aminopeptidase; Probably plays an important role in intracellular peptide degradation; Belongs to the peptidase M17 family. | 0.916 |
| ggt | pepD | STM3551 | STM0316 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Similar to E. coli aminoacyl-histidine dipeptidase (peptidase D) (AAC73341.1); Blastp hit to AAC73341.1 (485 aa), 92% identity in aa 1 - 485. | 0.948 |
| ggt | pepN | STM3551 | STM1057 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Similar to E. coli aminopeptidase N (AAC74018.1); Blastp hit to AAC74018.1 (870 aa), 94% identity in aa 1 - 870. | 0.908 |
| ggt | ybdK | STM3551 | STM0583 | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. | Putative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. | 0.940 |
| glyA | cysK | STM2555 | STM2430 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A; Two cysteine synthase enzymes are found, this enzyme and CysM; both catalyze the same reaction. Cysteine synthase B (CysM) can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. | 0.728 |
| glyA | gshB | STM2555 | STM3095 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Similar to E. coli glutathione synthetase (AAC75984.1); Blastp hit to AAC75984.1 (316 aa), 90% identity in aa 1 - 313. | 0.807 |
| glyA | pepA | STM2555 | STM4477 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.844 |
| glyA | pepB | STM2555 | STM2536 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Putative aminopeptidase; Probably plays an important role in intracellular peptide degradation; Belongs to the peptidase M17 family. | 0.823 |
| glyA | pepD | STM2555 | STM0316 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Similar to E. coli aminoacyl-histidine dipeptidase (peptidase D) (AAC73341.1); Blastp hit to AAC73341.1 (485 aa), 92% identity in aa 1 - 485. | 0.944 |
| glyA | pepN | STM2555 | STM1057 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). | Similar to E. coli aminopeptidase N (AAC74018.1); Blastp hit to AAC74018.1 (870 aa), 94% identity in aa 1 - 870. | 0.841 |
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