Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM0331Putative fumarylacetoacetate (FAA) hydrolase; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 34% identity in aa 11 - 217. (292 aa)    
Predicted Functional Partners:
STM0332
Putative hydrolase or acyltransferase; Similar to E. coli orf, hypothetical protein (AAC73780.1); Blastp hit to AAC73780.1 (254 aa), 33% identity in aa 15 - 129.
  
  
 0.984
leuD2
Putative 3-isopropylmalate isomerase (dehydratase), subunit with LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.961
leuC2
Putative 3-isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.915
STM0333
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74869.1); Blastp hit to AAC74869.1 (314 aa), 44% identity in aa 2 - 307; Belongs to the LysR transcriptional regulatory family.
  
    0.905
STM0328
Similar to E. coli putative transport protein (AAC74668.1); Blastp hit to AAC74668.1 (417 aa), 34% identity in aa 33 - 407.
  
    0.823
hpaH
4-hydroxyphenylacetate catabolism protein; Similar to E. coli 2-keto-4-pentenoate hydratase (AAC73453.1); Blastp hit to AAC73453.1 (271 aa), 34% identity in aa 6 - 261.
  
 
 0.704
hpaF
4-hydroxyphenylacetate catabolism protein.
  
 
  0.642
STM2177
Putative flutathione S-transferase; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 14 - 211.
  
  
 
0.631
hpaD
4-hydroxyphenylacetate catabolism protein.
  
    0.450
hpaA
4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 25% identity in aa 181 - 281.
  
  
 0.422
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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